NSAID’s in CRF

The relationship between NSAIDs and chronic renal failure is a bit tricky. We know they can cause acute renal injury but the association with CRF is not as clear. Cats with CRF treated with meloxicam have a longer life expectancy than those not treated as they are euthanised for their OA!

In some patients with stable stage 2 CRF we recommend NSAIDs for OA management, but monitor renal parameters two weeks after starting, then three monthly ongoing. It is important to educate owners that dosing when dehydrated may trigger acute renal failure, so it is best they contact you for alternative pain management strategies if their kitty is unwell.